Thursday, May 6, 2010

Broccoli 'could aid breast cancer fight' - scientists

Broccoli could hold the key to the fight against breast cancer, scientists believe.

A component of broccoli could help combat breast cancer, scientsts say

The vegetable, already hailed as a so-called "superfood", contains a chemical capable of targeting the cells which fuel the growth of tumours.

A component of broccoli called sulforaphane targets and kills cancer stem cells as well as preventing new tumours from growing, according to researchers at the University of Michigan.


Current chemotherapies do not work against cancer stem cells. Researchers believe that eliminating the cancer stem cells is key to controlling cancer.

The study, published in the journal Clinical Cancer Research, charts how scientists at the university's Comprehensive Cancer Centre tested the effects of sulforaphane in experiments involving mice and cell cultures.

Prof Duxin Sun, the author of the study, said: "Sulforaphane has been studied previously for its effects on cancer, but this study shows that its benefit is in inhibiting the breast cancer stem cells.

"This new insight suggests the potential of sulforaphane or broccoli extract to prevent or treat cancer by targeting the critical cancer stem cells."

Researchers took mice with breast cancer and injected varying concentrations of sulforaphane from the broccoli extract.

They then used several established methods to assess the number of cancer stem cells in the tumours.

These measures showed a marked decrease in the cancer stem cell population after treatment with sulforaphane, with little effect on the normal cells.

Cancer cells from mice treated with sulforaphane were also unable to generate new tumours.

The researchers then tested sulforaphane on human breast cancer cell cultures in the lab, finding similar decreases in the cancer stem cells.

Researchers are currently developing a method to extract and preserve sulforaphane.

The tests involved higher concentrations of sulforaphane than are available by simply eating broccoli.

Wednesday, May 5, 2010

Oil Slickonomics

“At its current leak rate of 5,000 barrels of oil per day, the spill could surpass the size of the 1969 Santa Barbara spill by next week. If the leak cannot be contained, it could exceed the size of the 1989 Exxon Valdez oil spill off Alaska by mid June.” Paul Harrison, Environmental Defense Fund
Three scenarios lie ahead. They rank as bad, worse, and ugliest (the latter being catastrophic and unprecedented). There is no “good” here.
The Bad.
Containment chambers are put in place and they catch the outflow from the three ruptures that are currently pouring 200,000 gallons of oil into the Gulf every day. If this works, it will take until June to complete. The chambers are 30-foot-high steel configurations that must be placed on the ocean floor at a depth of one mile. This has never been done before. If early containment is successful, the damages from this accident will be in the tens of billions. The cleanup will take years. The economic impact will be in the five states that have frontal coastline on the Gulf of Mexico: Texas, Louisiana, Mississippi, Alabama, and Florida.
The Worse.
The containment attempts fail and oil spews for months, until a new well can successfully be drilled to a depth of 13000 feet below the 5000-foot-deep ocean floor, and then concrete and mud are injected into the existing ruptured well until it is successfully closed and sealed. Work on this approach is already commencing. Timeframe for success is at least three months. Note the new well will have to come within about 20 feet of the existing point where the original well enters the reservoir at a distance of 3.5 miles from the surface drilling rig. Damages by this time may be measured in the hundreds of billions. Cleanup will take many, many years. Tourism, fishing, all related industries may be fundamentally changed for as much as a generation. Spread to Mexico and other Gulf geography is possible.
The Ugliest.
This spew stoppage takes longer to reach a full closure; the subsequent cleanup may take a decade. The Gulf becomes a damaged sea for a generation. The oil slick leaks beyond the western Florida coast, enters the Gulfstream and reaches the eastern coast of the United States and beyond. Use your imagination for the rest of the damage. Monetary cost is now measured in the many hundreds of billions of dollars.
Some thoughts about markets and impacts.
Usually, the first estimates in any crises are too low. That is true here. 1000 barrels a day is now 5000, and some estimates of spillage are trending higher. No one knows exactly. The containment and boom mechanism is subject to weather cooperation as we can see this weekend. Soon we are entering the hurricane season. The thoughts of a storm stirring up the Gulf, hampering any cleanup or remediation drilling effort and creating a huge 10,000 square mile black stew is frightening to every professional in the business.
This will be a financial calamity for many firms, not just BP and its partners and service providers. Their liabilities are immense and must not be underestimated. The first estimate of $12.5 billion is only a starter.
Thousands of small and independent businesses as well as larger public companies in tourism are hurt here. This is not just about the source of half the nation’s shrimp. That is already a casualty. It’s also about the bank loans for the $200,000 shrimp boat and the house the boat owner and/or his employees live in and the fact that this shock piles on a fragile financial system that is trying to recover from a three-year financial crisis. Case study, my fishing guide in the Everglades splits his time between Florida and Louisiana. His May bookings in LA have cancelled. His colleagues lost theirs and their lodge will be empty. They are busy trying to find work in the clean up. For him, his wife and eleven year old daughter, his $600 a day guide fees just went “poof”. When I asked him if he thought he had a legal claim on BP, he said he hadn’t thought about it yet but it gave him pause. As we suggested above, the $12.5 billion loss estimate is only a starter.
Federal deficit spending will certainly rise by tens, and maybe hundreds, of billions as emergency appropriations are directed at larger and larger efforts to clean up this mess. At the same time, federal and state revenues tied to Gulf-region businesses will fall. My colleague John Mousseau will be discussing the impact on state and local government debt in a separate research commentary.
We expect that the Federal Reserve will extend the timeframe that we have come to know as the “extended period” in the making of its monetary policy. We do not expect the Fed to raise interest rates at all for the rest of this year, and maybe well into next year. We expect to see the deterioration of the economic statistics for the US to reveal the onset of this oil-slick crisis in May, and the negative impact will intensify during the summer months. A “double-dip” recession probably has been made more likely by this tragedy.
We are at the highest level of cash in our US stock accounts that we have seen in over a year and a half. We expect a market correction will present entry points at lower stock prices. We have exited the financial sectors, including the insurance ETF. We now worry about the banks that are exposed. We do not own the major oil stocks now. Some of them face enormous liability payments.
In addition, the offshore-drilling energy sector will face much-increased and more costly regulation. Deepwater and all offshore drilling in the US has been set back for a generation, just as Three Mile Island set back nuclear power development for decades. No politician can win an election now with a permissive view on drilling. Sarah Palin’s “Drill, baby, drill” now condemns her to political marginalization. Off shore drilling has lurched to the top of the political agenda in this November’s election cycle.

Louisiana Oil Spill: Feds Gave Safety Prize to Transocean's Deepwater Horizon

The federal agency charged with enforcing safety on deepwater oil rigs has also played a major role in promoting the industry's claim that it is safe, and in 2009 handed out one of its top prizes for safety to Transocean's Deepwater Horizon.

Crews are trying something new to prevent damage.

Transocean's safety effort included two dance videos, one of them a hip-hop video promoting safety that was filmed on the Deepwater Horizon. The Deepwater Horizon exploded last week, killing 11 and unleashing what could become one of the worst oil spill disasters in the nation's history.

The Minerals Management Service, which falls under the U.S. Department of Interior, touts the recipients in government press releases and hosts an awards luncheon at a lavish industry association conference in Houston. This year's luncheon was scheduled for Monday before it was abruptly canceled.

"The ongoing situation with the Transocean Deepwater Horizon drilling accident has caused the MMS to dedicate considerable resources to the successful resolution of this event which will conflict with holding this ceremony next week," a statement released on the conference web site says. " The MMS will announce an alternative plan during the next several weeks."

MMS issued its SAFE award to Transocean for its performance in 2008, crediting the company's "outstanding drilling operations" and a "perfect performance period." Transocean spokesman Guy Cantwell told ABC News the awards recognized a spotless record during repeated MMS inspections, and should be taken as evidence of the company's longstanding commitment to safety.

One element of Transocean's safety campaign was a campy, and now somewhat macabre, music video that was filmed on the decks of the Deepwater Horizon rig. The video uses hip-hop songs to encourage workers to "keep your hands clear" while performing tasks. In one scene, workers in red jump suits dance on the platform's helipad.

A second video shows Transocean President and COO Steven Newman making good on a promise to do a dance if the India division had the best safety record in the company two years in a row. Newman and backup dancers perform to the sounds of music from an Indian movie at a company meeting in Mumbai in February 2009.

CLICK HERE TO WATCH THE DANCE VIDEOS

5/3/10 Ron Paul and Alan Grayson with Dylan Ratigan: Audit the Fed!

Click this link ...... http://eclipptv.com/viewVideo.php?video_id=11724

April 2010 cooler than April 1998

earth-with-satellite

News: the RSS AMSU data for April 2010 are out. The anomaly, 0.546, is the lowest one for 2010 so far. It is the second warmest April on their record but it's more than 0.3 °C cooler than April 1998 and April 2005 was just a bit cooler than April 2010.

Originally posted on May 1st

When you look at the daily UAH AMSU temperatures for April 2009 and April 2010, you will find out that the near-surface average brightness temperature for April 2010, -15.50 °C, was 0.4 °C warmer than that of April 2009, which was -15.90 °C.

That's a substantial year-on-year warming. However, with the anomaly around 0.55 °C using these centidegree conventions, as well as with the anomaly around 0.48 °C using these millidegree conventions, April 2009 will be the coolest month of 2010 so far.

It will be calculated to be the second warmest April on the UAH record, after April 1998 which remains the hottest month since 1978 when the UAH records began (and probably for a few centuries, too). The UAH anomaly in April 1998 was 0.76 or 0.77 °C, respectively, so the April 2010 anomaly will still be a whopping 0.2 or 0.3 °C cooler than April 1998.

The El Nino has weakened but the El Nino conditions continue and will continue through the summer. The year 2010 is likely to end up pretty close to 1998, the warmest year on the UAH record so far.

Note: the daily data contain some systematic error - because they use a "wrong" satellite - so they're not the best ones that the UAH team uses for their official figures now. But they're the best data that are instantly available on the daily basis. Sorry for the mess with the multiple datasets, it's not my fault. Because of these and various errors and confusions, my estimates must be understood as figures with a 0.05 °C error margin.

BP Offering 5000 Dollars To Gulf Residents If They Agree Not To Sue!

Click this link ..... http://eclipptv.com/viewVideo.php?video_id=11725

The Rich Continue To Use Government To Cut Out Their Competition

One of the scams that the rich use the government for in order to stop less wealthy people from getting richer is to promote the lie that, since venture capital is “riskier” than investing in public securities on the NYSE (another lie), individuals with less than a certain minimum net worth should not be allowed to invest in these “riskier” VC investments. Bankster puppet Sen. Chris Dodd (D-CT) has inserted into the upcoming financial “reform” bill a clause that would more than double the minimum net worth of a potential venture capital investor from $1 million to $2.5 million, or require an annual salary of $450,000 for the past two years to the current annual salary requirement of $200,000 [the article mistakenly says it is $250,000] for the past two years. (Here is a link to the current minimum net worth regulations.)

Putting aside the libertarian principle that my money is my property and, therefore—just like the property of my body—it is up to me to decide what I want to do with it as far as my personal subjective risk is concerned, an important issue here is that this new rule forcibly prevents people from investing in an area that not only can bring them much higher returns than publicly-traded stocks, but it cuts down the supply of investment funds for smaller, innovative new firms which generally find it much more difficult to raise funds compared to an established big corporation—because the start-up firms’ products have not yet proven themselves in the marketplace. The bill insert also requires that a start-up firm wait up to four months to get permission from the Bankster-controlled SEC to accept the investment funds. And, get this:

“…this proposed bill also seeks to change the rules for a federal pre-emption []sic] for state regulation. Under the proposed bill, start-ups would be subject to state regulations from the 50 different states. Right now, start-ups & investors are not subject to 50 different state regulators. This would likely lead to more cost & risk for the start-up.” [emphasis mine]

Yes, this is just what our depressed economy needs now—even less businesses to employ people and provide new products to improve our lives.

[Thanks to Shelly Roche]